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AAD guidelines take cSCC disease management as the core concept, and put forward Suggestions in aspects of cSCC clinical information collection, histological evaluation and treatment, etc., especially emphasizing standardized multidisciplinary comprehensive treatment and management, aiming to provide the best and most appropriate individual treatment scheme for cSCC patients.However, most of the recommended schemes are only based on retrospective studies of head and neck squamous cell carcinoma, expert consensus and recommended evidence, and the quality and quantity of evidence are insufficient. Therefore, a large number of high-quality prospective, multi-center clinical studies are still needed to further confirm and promote them.